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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
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Spelling variations of this family name include: Lieb, Liebe, Lieber, Liber and others. He fought at Waterloo in Another 37 words 3 lines of text are included under the topic Early Lieber Notables in all our PDF Extended History products and printed products wherever possible. Digital Products on Checkout, all other products filled in 1 business day.

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lieber. comparative degree of gern; rather, better, by preference. Ich nehme lieber das Fahrrad als das Auto. I would rather take the bicycle than the car. German to English translation results for 'lieber' designed for tablets and mobile devices. Possible languages include English, Dutch, German, French, Spanish.

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André Lieber, MD, PhD

Create File. Annu Rev Biochem. Lieber MR 1.

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Physiologic and pathologic causes of double-strand breaks in mammalian somatic cells are listed at the top. During S and G2 of the cell cycle, homology-directed repair is common because the two sister chromatids are in close proximity, providing a nearby homology donor.

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Proteins involved in the repair pathways are listed. Flexibility in the loading of these enzymatic components, the option to load repeatedly iteratively , and independent processing of the two DNA end all permit mechanistic flexibility for the NHEJ process. In addition to the overall mechanistic flexibility, each component exhibits enzymatic flexibility and multifunctionality, as discussed in the text. Physical interactions between NHEJ components are summarized.

Ku is a heterodimer of Ku70 and